Serum Proteins in Teyroii)
نویسندگان
چکیده
Abnormalities in the serum proteins have been described in several disorders of thyroid function (Man et al., 1940; Lewis and McCullagh, 1944; Lamberg and Grasbeck, 1955) and in particular in auto-immune thyroiditis, where a raised serum y-globulin has been found (Fromm et al., 1953; Luxton and Cooke, 1956; Skillern et al., 1956; Doniach and Hudson, 1957; Greene et al., 1958; Roitt et al., 1958 ; Hetz et al., 1959; Shulman et al., 1960). The diagnostic significance of these changes is difficult to evaluate because in most studies the number of patients has been small. Furthermore, the control series of normal subjects and of patients with other forms of thyroid disease has been inadequate for statistical evaluation. In this paper we report a detailed study of the serum protein abnormalities in 182 patients with different thyroid disorders and compare them with those found in 26 normal controls. In addition the diagnostic value of the serum flocculation tests and the erythrocyte sedimentation rate (E.S.R.) has been studied, since both have been suggested as diagnostic aids in auto-immune thyroiditis (Luxton and Cooke, 1956; Doniach and Hudson, 1957; Hubble, 1959).
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